Absolute Structure Determination in Absence of Heavy Scatterers |
| J. Grochowski Regional Laboratory of Physicochemical Analysis and Structural Research, Jagiellonian University, Ingardena 3, 30-060 Kraków, Poland |
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| Methods of absolute structure determination for molecules containing only light atoms (C, H, N, O) are discussed in the paper. This experimentally difficult problem has a direct application in the structure determination of naturally originated compounds and modern chiral drugs. Several experimental methods of absolute structure determination like electron diffraction, multiple X-ray diffraction and X-ray anomalous scattering techniques are briefly discussed and compared. An application of dedicated azimuthal scan method for the case of hexamethylenetetramine is given as an illustration of this technique. |
| DOI: 10.12693/APhysPolA.91.745 PACS numbers: 61.10.Nz, 61.10.Yh, 33.15.Bh |