Tri-calcium Phosphate (Nanoparticles/Nanofibers)/PVA for Bone Tissue Engineering |
| Furqan S. Hashim, Mukhlis M. Ismail, Wafaa A. Hussain
Department of Applied Sciences, University of Technology, Baghdad, Iraq |
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| Porous poly (vinyl alcohol) scaffold samples were fabricated using nanoparticles and nano-fibers of tri-calcium phosphate, which were added separately to the scaffolds with two ratios 0.05 and 0.25, respectively. Then, the results obtained were compared. The surface morphology and spectrum were examined by scanning electron microscope and Fourier transform infrared spectroscopy. The phase composition by X-ray diffraction was also examined to prove the bioactivity of the scaffold. The biodegradation, mechanical properties, porosity, density, and swelling were also tested. The impact of the strength values was enhanced significantly from 3.89 to 13.24 kJ/m2 by using the nano-fibers of tri-calcium phosphate. However, the porosity of the tri-calcium phosphate nano-particles was higher than the tri-calcium phosphate nano-fibers by up to 62%. In fact, the porosity values in nano-fibers tri-calcium phosphate were also acceptable in comparison with the natural human bone. The samples show the highest percentage of 43% in losing weight in the G5 after incubation in phosphate buffer saline for the biodegradation test. |
DOI:10.12693/APhysPolA.140.337 topics: bone tissue engineering, PVA scaffold, nanoparticles, nano fibers |