Effect of UV Radiation Applied Fractionally or Continuously on Stability of Biosensor Receptor Layer Component
A. Kłos-Witkowska, K. Kajstura
Faculty of Mechanical Engineering and Computer Science, Department of Computer Science and Automatics, University of Bielsko-Biala, Willowa 2, 43-309 Bielsko-Biala, Poland
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This work includes an examination report of the influence of external conditions on the stability of the receptor layer cross-linking component in biosensors. Observations and three types of analysis resulting from the conducted research are presented. The studies described the influence of UV radiation (fractional: 1×5 min, 2×5 min, 3×5 min and continuous 5 min, 10 min, 15 min) exposure. A new type of analysis was carried out to compare the impact of external factors affecting the stability of the receptor layer cross-linking component in biosensors. An approach of numerical interpretation of the qualitative changes of stability has been offered. The tested factors influence the stability of the tested substance. All applied factors reduce the stability of the biosensors receptor layer component, however the dynamics of changes occurring under the influence of various types of UV application are different. It has been observed and confirmed by analyses that the effects caused by the external factor depend on the way of application (continuous or fractional exposure) and time of irradiation.

DOI:10.12693/APhysPolA.138.781
topics: biosensor, BSA, UV/Vis, receptor layer