Nanoparticles Coated by Porous SiO2: Core@Shell Nanosystems for Biomedical Applications
J. Szücsováa, A. Zeleňákováa, O. Kapustaa, J. Bednarčíka, b, V. Kavečanskýb, V. Girmana, V. Zeleňákc
aPavol Jozef Šafárik University in Košice, Faculty of Science, Department of Condensed Matter Physics, Park Angelinum 9, 040 01 Košice, Slovakia
bSlovak Academy of Science, Institute of Experimental Physics, Watsonova 47, 040 01 Košice, Slovakia
cPavol Jozef Šafárik University in Košice, Faculty of Science, Department of Inorganic Chemistry, Moyzesova 11, 040 01 Košice, Slovakia
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Magnetic based nanosystems can be used for diagnostic and imaging techniques or can help in the treatment process by acting as a drug carrier in intelligent drug delivery systems. For such applications, these systems must be stable, biocompatible, with reasonable magnetic properties and non-invasive in relation to living organisms. Among others, core@shell platforms are widely used for these purposes. Therefore, we have prepared composites consisting of Fe3O4 magnetic core and SiO2 biocompatible shell through a combination of self-assembly and co-precipitation techniques. The systems with three different core sizes were prepared and subsequently coated with porous SiO2. Afterwards, the magnetic properties of prepared samples were investigated in the temperature range 2-350 K using a SQUID-based magnetometer. Structure, size, and morphology were characterized by X-ray diffraction and transmission electron microscopy methods. Our experimental study confirms that the magnetic properties of studied systems are affected by the size of particles. It has been shown that smaller particles exhibit lower values of magnetic moment. We have confirmed the dominance of the ferromagnetic phase in uncoated Fe3O4 magnetic core, while on the other hand, the superparamagnetic phase increases and became substantial in coated Fe3O4mSiO2 composites.

DOI:10.12693/APhysPolA.137.733
topics: magnetic nanoparticles, mesoporous silica, core@shell, drug delivery