Comparison of Magnetic and Non-Magnetic Nanoparticles as Sonosensitizers in Ultrasonic Hyperthermia |
| K. Kaczmarek, R. Bielas, M. Siluk, T. Hornowski, A. Józefczak
Institute of Acoustics, Faculty of Physics, Adam Mickiewicz University in Poznań, Uniwersytetu Poznańskiego 2, 61-614 Poznań, Poland |
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| Nanoparticles have attracted a great interest in scientific world because of the new applications they offer. They are commonly used in medical procedures such as hyperthermia and thermal ablation. Here, we propose, using magnetic and non-magnetic nanoparticles, as sonosensitizers which are the materials that improve the efficiency of heating induced by ultrasound. A comparison between various types of nanomaterials, such as magnetite, silicon dioxide, and Laponite nanoparticles, was done. The results show that both magnetic and non-magnetic nanomaterials can be utilized in ultrasonic heating. However, magnetite nanoparticles without surface modification can strongly interact with each other and are prone to agglomeration that can deteriorate thermal effect in tissue-mimicking phantoms. |
DOI:10.12693/APhysPolA.137.653 topics: magnetic nanoparticles, ultrasonic hyperthermia, sonosensitizers, specific absorption rate |