Biological Action in and out of the Water Window |
| L. Vyšína,b, M. Davídková c, P. Wachulak d, H. Fiedorowicz d, A. Bartnik d, M. Krůse,a, M. Kozlováa,e, J. Skálaa,e, J. Dostále,a, R. Dudžáka,e and L. Juhaa,e
aInstitute of Physics of the CAS, Na Slovance 2, 182 21 Prague 8, Czech Republic bFNSPE, Czech Technical University in Prague, Břehová 7, 115 19 Prague 1, Czech Republic cNuclear Physics Institute of the CAS, Řež 130, 250 68 Řež, Czech Republic dInstitute of Optoelectronics, Military University of Technology, S. Kaliskiego 2, 00-908 Warsaw, Poland eInstitute of Plasma Physics of the CAS, Za Slovankou 3, 182 00 Prague 8, Czech Republic |
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| This study is dealing with the difference of radiation chemical yields of single and double strand breaks induced in plasmid DNA by photons inside and outside of the soft X-ray water window, i.e., in the wavelength range from 2.28 nm to 4.88 nm. Photons were generated by various plasma sources providing nanosecond and sub-nanosecond pulses of extreme ultraviolet, soft X-ray and X-ray radiation. DNA strand breaks were determined by agarose gel electrophoresis. Higher radiation chemical yields of both single and double strand breaks were found using picosecond and nanosecond sources of extreme ultraviolet and X-ray radiation. |
DOI: 10.12693/APhysPolA.133.296 PACS numbers: 87.14.G-, 52.38.-r |