Comparison of Iron Oxide-Related MRI Artifacts in Healthy and Neuropathological Human Brain Tissue
M. Masarovaa, A. Krafcik a, M. Teplan a, O. Strbaka,b, D. Gogola a, P. Boruta c, D. Dobrota b and I. Frollo a
aInstitute of Measurement Science, SAS, Dubravska cesta 9, 841 05 Bratislava, Slovakia
bBiomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Mala Hora 4, 036 01 Martin, Slovakia
cSlovak Medical University, Limbova 12, 833 03 Bratislava, Slovakia
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The aim of this study is to clarify whether clinical magnetic resonance imaging data can be utilised to evaluate the pathological processes associated with disrupted iron homeostasis, such as neurodegenerative processes or cirrhosis. Although MRI has the potential to become a non-invasive biomarker of such pathology, new quantification methods must be introduced. Our findings confirmed that it is possible to detect significant difference between healthy and pathological tissue from standard T2 weighted MRI protocols.

DOI: 10.12693/APhysPolA.131.1108
PACS numbers: 87.61.Ff, 75.50.Cc, 87.19.xr, 87.19.xe