Morphological Variations of Chondrocytes in Bovine Articular Cartilage Using Confocal Laser Scanning Microscopy
E. Çıçek and A. Arikanoğlu
Faculty of Science and Art, Mehmet Akif Ersoy University, Burdur, Turkey
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Articular cartilage is a highly organized avascular tissue, a matrix consisting of a three-dimensional meshwork of type II collagen fibrils and proteoglycans. To understand the effects of the alteration in chondrocyte shape in response to physiological load in local mechanical properties and, thus, to contribute to experimental load studies, we studied variation of the natural load induced deformations in chondrocytes among five different regions from bovine articular cartilage samples using confocal laser scanning microscopy imaging methods. The morphological differences of the chondrocyte shape, orientation and circularity in articular cartilage were measured. The chondrocytes were observed to be smoother in more loaded regions to the center of the cartilage.

DOI: 10.12693/APhysPolA.125.898
PACS numbers: 87.85.G-