Point Investigation Method for Cancer Changed Tissues
Ł. Kłonowskia, Z. Kulasa, E. Bereś-Pawlika, M. Rzącab, R. Czarneckib and Z. Grzebieniakc
aInstitute of Telecommunications, Teleinformatics and Acoustics, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland
bOncology Department, Regional Specialistic Hospital, Kamińskiego 73a, 51-124 Wrocław, Poland
cOncology Department, Academy Clinical Hospital, Borowska 213, 50-556 Wrocław, Poland
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In this paper we describe the method of point investigation for cancer changed tissues with application of fluorescence phenomenon. The measurements have been made using a specially constructed scanning setup and fiber sensors. The experiment with investigation of endogenous fluorescence has been made on different types of slide tissues (e.g. breast and intestine tumor or precancerous and pathological skin tissues). The obtained spectral characteristics of fluorescence, with typical intensity peaks in 480-520 nm range, have explicitly outlined healthy and pathologically changed areas. The intensity of detected fluorescence determines the evaluation of disease advancement. Moreover, the ability to scan the surface of a tissue sample with constantly moving step of scanning setup in X-Y axis allows us to present the results in a spatial distribution of fluorescence intensity.
DOI: 10.12693/APhysPolA.118.1174
PACS numbers: 87.57.-s, 87.57.R-, 87.57.nm, 87.19.xu, 87.19.xj