Challenges in Biology and Medicine with Synchrotron Infrared Light |
| P. Dumas a, L.M. Miller b and M.J. Tobin c
a SOLEIL Synchrotron, Saint-Aubin, BP 48, 91192 Gif-sur-Yvette Cedex, France b National Synchrotron Light Source, Brookhaven National Laboratory, Upton, NY 11973, USA c Australian Synchrotron Project, 800 Blackburn Road, Clayton Victoria, Australia |
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| The brightness (or brilliance) of synchrotron radiation was exploited in infrared microspectrosocopy. Among application of this synchrotron-based microanalytical technique, biological and biomedical investigations, at the diffraction-limited spot size, are exhibit of an increasing interest among almost all the existing infrared beamline worldwide. This paper is presenting the main properties of such a source, coupled with an infrared microscope. Several important applications in biomedical field are reported: cancer cells studies and drug effects, human substantia nigra in Parkinson's disease, β-amyloids deposits in Alzheimer's disease. |
| DOI: 10.12693/APhysPolA.115.446 PACS numbers: 87.80.Dj, 87.80.-y, 87.64.km, 87.56.B-, 87.19.xj, 87.16.-b, 87.15.bd, 78.30.-j |