Magnetic Properties of Encapsulated Magnetite in PLGA Nanospheres |
| M. Koneracká, V. Závišová, M. Timko, P. Kopčanský, N. Tomašovičová and K. Csach
Institute of Experimental Physics, Slovak Academy of Sciences, Watsonova 47, 04001 Košice, Slovakia |
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| Received: 9 07 2007; |
| In this study, the biocompatible magnetic fluid was encapsulated in biodegradable polymer PLGA (poly D, L/lactide-co-glycolide acid) by the nanoprecipitation method. We characterized these spheres in terms of morphology, magnetite content and magnetic properties. The results showed good encapsulation with magnetite content 22wt% and magnetization 3.4 mT. The transmission electron microscopy and scanning electron microscopy images showed that magnetic particles have almost a spherical shape with approximate size 250 nm. Infrared spectroscopy and thermogravimetric analysis measurements were used to confirm incorporation of magnetic particles into the PLGA polymer. |
| DOI: 10.12693/APhysPolA.113.595 PACS numbers: 71.20.Rv, 75.50.Mm, 87.83.+a |